{"id":1987,"date":"2024-06-04T13:17:53","date_gmt":"2024-06-04T11:17:53","guid":{"rendered":"http:\/\/www1.up.poznan.pl\/kzcid\/?p=1987"},"modified":"2024-06-04T13:46:51","modified_gmt":"2024-06-04T11:46:51","slug":"nowa-publikacja-rozdzial-w-ksiazce","status":"publish","type":"post","link":"http:\/\/www1.up.poznan.pl\/kzcid\/aktualnosci\/nowa-publikacja-rozdzial-w-ksiazce\/","title":{"rendered":"Nowa publikacja &#8211; rozdzia\u0142 w ksi\u0105\u017cce"},"content":{"rendered":"<p><span class=\"x193iq5w xeuugli x13faqbe x1vvkbs x1xmvt09 x1lliihq x1s928wv xhkezso x1gmr53x x1cpjm7i x1fgarty x1943h6x xudqn12 x3x7a5m x6prxxf xvq8zen xo1l8bm xzsf02u x1yc453h\" dir=\"auto\">Epigenetic Control and Obesity<\/span><\/p>\n<p>Agata Chmurzy\u0144ska<\/p>\n<p>Abstrakt<\/p>\n<p>Overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. These are among the greatest public health problems worldwide, as excess weight is a risk factor for numerous conditions, including diabetes, hypertension, stroke, and heart disease. In the general population overweight has a complex architecture, which means that it depends on genetic and environmental factors and on the interactions between them. Increasing evidence suggests that DNA methylation and other epigenetic mechanisms are involved in development and progression of obesity. Epigenome-wide association studies (EWAS) identified numerous loci associated with obesity or with the results on weight-loss interventions. However, heterogeneity in study design and analysis limits overlap in the results. Different types of non-coding RNAs have also been related to obesity as they are involved in stimulation or inhibition of adipogenesis and regulation of its metabolic and endocrine functions. The identification of reliable and reproducible epigenetic biomarkers for obesity and response to weight-loss therapies remains challenging.<\/p>\n<p>rozdzia\u0142 w ksi\u0105\u017cce: Vaschetto, L.M. (eds) Molecular Mechanisms in Nutritional Epigenetics. Epigenetics and Human Health, Springer, Cham, doi.org\/10.1007\/978-3-031-54215-2_10<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Epigenetic Control and Obesity Agata Chmurzy\u0144ska Abstrakt Overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. These are among the greatest public health problems worldwide, as excess weight is a risk factor for numerous&hellip;&nbsp;<a href=\"http:\/\/www1.up.poznan.pl\/kzcid\/aktualnosci\/nowa-publikacja-rozdzial-w-ksiazce\/\" class=\"more-link\">Czytaj dalej<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[20],"tags":[],"_links":{"self":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1987"}],"collection":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/comments?post=1987"}],"version-history":[{"count":4,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1987\/revisions"}],"predecessor-version":[{"id":1991,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1987\/revisions\/1991"}],"wp:attachment":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/media?parent=1987"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/categories?post=1987"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/tags?post=1987"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}