Effects of dietary seaweed on obesity-related metabolic status: a systematic review and meta-analysis of randomized controlled trials<\/p>\n
Karolina \u0141agowska, Adam Jurgo\u0144ski, Mari Mori, Yukio Yamori, Shigeru Murakami, Takashi Ito, Toshiya Toda, Joanna Maria Pieczy\u0144ska-Zaj\u0105c, Joanna Bajerska<\/p>\n
Abstrakt<\/p>\n
Context: Seaweed is a promising source of anti-obesity agents, including polysaccharides, proteins, polyphenols, carotenoids, and n-3 long-chain polyunsaturated fatty acids. The anti-obesity effects of such compounds may be due to several mechanisms, including inhibition of lipid absorption and metabolism, effect on satiety, and inhibition of adipocyte differentiation.
\nObjective: The aim of this study was to assess the evidence from human randomized controlled trials for the effects of seaweed on body-weight status as well as lipid and nonlipid parameters in adults with overweight and obesity.
\nData sources: Four databases-Medline, Scopus, Web of Science, and Cochrane Library-were searched from December 2022 to June 2023 using the following key words: Seaweed OR fucoxanthin OR alginates OR fucoidans OR phlorotannin’s OR macroalgae OR marine algae AND obesity OR overweight OR BMI OR body mass index.
\nData extraction: Eleven interventional studies (10 parallel and 1 crossover) were extracted.
\nData analysis: Meta-analysis showed a significant effect, favoring the intervention group for BMI (body mass index) (standardized mean difference [SMD]: -0.40; 95% CI: -0.65 to -0.16 kg\/m2; P = 0.0013) and percentage of fat mass (SMD: -1.48; 95% CI: -2.66% to -0.30%, P = 0.0138). The results were seen when refined or extracted brown seaweed (BMI) or only refined brown seaweed (% fat mass) were administered to participants for at least 8 weeks. Moreover, a significant overall effect of seaweed supplementation on total cholesterol (SMD: -7.72; 95% CI: -12.49 to -2.95 mg\/dL; P = 0.0015) and low-density-lipoprotein cholesterol (SMD: -7.33; 95% CI: -11.64 to -3.02 mg\/dL; P < 0.001) was noted. Any significant effects of seaweed on glucose metabolism were not shown.
\nConclusion: Edible seaweed supplementation shows potential for managing obesity and disorders of the blood lipid profile when administered to participants for at least 8 weeks.
\nSystematic review registration: PROSPERO registration no. CRD42022378484 (www.crd.york.ac.uk\/PROSPERO).<\/p>\n
S\u0142owa kluczowe: alginate; brown seaweeds; fucoidan; fucoxanthin; obesity; overweight<\/p>\n
Nutrition Reviews, nuae042, https:\/\/doi.org\/10.1093\/nutrit\/nuae042<\/p>\n","protected":false},"excerpt":{"rendered":"
Effects of dietary seaweed on obesity-related metabolic status: a systematic review and meta-analysis of randomized controlled trials Karolina \u0141agowska, Adam Jurgo\u0144ski, Mari Mori, Yukio Yamori, Shigeru Murakami, Takashi Ito, Toshiya Toda, Joanna Maria Pieczy\u0144ska-Zaj\u0105c, Joanna Bajerska Abstrakt Context: Seaweed is… Czytaj dalej<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[20],"tags":[],"_links":{"self":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1956"}],"collection":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/comments?post=1956"}],"version-history":[{"count":1,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1956\/revisions"}],"predecessor-version":[{"id":1957,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1956\/revisions\/1957"}],"wp:attachment":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/media?parent=1956"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/categories?post=1956"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/tags?post=1956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}