{"id":1800,"date":"2024-01-12T10:29:07","date_gmt":"2024-01-12T09:29:07","guid":{"rendered":"http:\/\/www1.up.poznan.pl\/kzcid\/?p=1800"},"modified":"2024-01-12T10:29:07","modified_gmt":"2024-01-12T09:29:07","slug":"nowa-publikacja-35","status":"publish","type":"post","link":"http:\/\/www1.up.poznan.pl\/kzcid\/aktualnosci\/nowa-publikacja-35\/","title":{"rendered":"Nowa publikacja"},"content":{"rendered":"<p><strong>Serum lactoferrin levels in abdominal obese postmenopausal women with normal bone status and osteopenia<\/strong><\/p>\n<p>Ma\u0142gorzata Jamka1, Edyta M\u0105dry2, Patrycja Krzy\u017canowska-Jankowska1, Joanna Bajerska3, Pawe\u0142 Bogda\u0144ski4, Aleksandra Lisowska5, Jaros\u0142aw Walkowiak1<\/p>\n<p><sup>1<\/sup>Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poland<sup><br \/>\n2<\/sup>Department of Physiology, Poznan University of Medical Sciences, Poland<sup><br \/>\n3<\/sup>Department of Human Nutrition and Dietetics, Pozna\u0144 University of Life Sciences, Poland<sup><br \/>\n4<\/sup>Department of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznan University of Medical Sciences, Poland<sup><br \/>\n5<\/sup>Department of Pediatric Diabetes, Auxology and Obesity, Poznan University of Medical Sciences, Poland<\/p>\n<p><strong>Background.\u00a0<\/strong>Recently, it has been shown that lactoferrin intake might impact bone health. However, less is known about the association between blood lactoferrin levels and bone status. Therefore, this study aimed to compare serum lactoferrin concentrations between abdominally obese postmenopausal women with normal bone health and osteopenia.<br \/>\n<strong>Material and methods.\u00a0<\/strong>A total of 238 women aged 50\u201375 years with a body mass index (BMI) \u2265 30 kg\/m2 and waist circumference \u2265 88 cm were included in the study. Their bone mineral density (BMD) and content (BMC) for the total body, lumbar spine and femoral neck were measured using the dual-energy X-ray absorptiometry method, and the T-score and Z-score were calculated. Biochemical markers of glucose and insulin homeostasis, lipid metabolism and inflammatory parameters, lactoferrin levels, and body composition were determined.<br \/>\n<strong>Results.\u00a0<\/strong>Women with a T-score of the lumbar spine &gt; \u20131 were significantly younger (<em>p\u00a0<\/em>= 0.0005) and had a higher body weight (<em>p\u00a0<\/em>= 0.0208) and BMI (<em>p\u00a0<\/em>= 0.0312) than participants with a T-score \u2264 \u20131. In the group of subjects with a T-score &gt; \u20131, BMC at the lumbar spine was significantly higher in women with lactoferrin levels below than above the median (<em>p\u00a0<\/em>= 0.0455), whereas in the group of those with a T-score \u2264 \u20131, women with lactoferrin levels lower than the median had significantly lower BMC (<em>p\u00a0<\/em>= 0.0298), BMD (<em>p\u00a0<\/em>= 0.0428), T-score (<em>p\u00a0<\/em>= 0.0216) and Z-score (<em>p\u00a0<\/em>= 0.0452) at the femoral neck and BMC (<em>p\u00a0<\/em>= 0.0358), BMD (<em>p\u00a0<\/em>= 0.0244) and T-score (<em>p\u00a0<\/em>= 0.0139) at the total body.<br \/>\n<strong>Conclusion.\u00a0<\/strong>These results suggest that serum lactoferrin levels might be associated with bone health, but the effect may differ in subjects with normal bone status and osteopenia.<\/p>\n<p>Acta Sci.Pol. Technol. Aliment. 22.3 (2023): 279-292. https:\/\/doi.org\/10.17306\/J.AFS.2023.1177<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Serum lactoferrin levels in abdominal obese postmenopausal women with normal bone status and osteopenia Ma\u0142gorzata Jamka1, Edyta M\u0105dry2, Patrycja Krzy\u017canowska-Jankowska1, Joanna Bajerska3, Pawe\u0142 Bogda\u0144ski4, Aleksandra Lisowska5, Jaros\u0142aw Walkowiak1 1Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences,&hellip;&nbsp;<a href=\"http:\/\/www1.up.poznan.pl\/kzcid\/aktualnosci\/nowa-publikacja-35\/\" class=\"more-link\">Czytaj dalej<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[20],"tags":[],"_links":{"self":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1800"}],"collection":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/comments?post=1800"}],"version-history":[{"count":1,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1800\/revisions"}],"predecessor-version":[{"id":1801,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1800\/revisions\/1801"}],"wp:attachment":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/media?parent=1800"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/categories?post=1800"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/tags?post=1800"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}