{"id":1448,"date":"2022-12-09T16:41:49","date_gmt":"2022-12-09T15:41:49","guid":{"rendered":"http:\/\/www1.up.poznan.pl\/kzcid\/?p=1448"},"modified":"2022-12-09T16:41:49","modified_gmt":"2022-12-09T15:41:49","slug":"nowa-publikacja-20","status":"publish","type":"post","link":"http:\/\/www1.up.poznan.pl\/kzcid\/aktualnosci\/nowa-publikacja-20\/","title":{"rendered":"Nowa publikacja"},"content":{"rendered":"<p>The Impacts of Combined Blood Flow Restriction Training and Betaine Supplementation on One-Leg Press Muscular Endurance, Exercise-Associated Lactate Concentrations, Serum Metabolic Biomarkers, and Hypoxia-Inducible Factor-1\u03b1 Gene Expression<\/p>\n<p>Steven B. Machek, Dillon R. Harris, Emilia E. Zawieja, Jeffery L. Heileson, Dylan T. Wilburn, Anna Radziejewska, Agata Chmurzynska, Jason M. Cholewa, Darryn S. Willoughby<\/p>\n<section id=\"html-abstract\" class=\"html-abstract\">\n<div class=\"html-p\">The purpose of this investigation was to compare the impacts of a potential blood flow restriction (BFR)-betaine synergy on one-leg press performance, lactate concentrations, and exercise-associated biomarkers. Eighteen recreationally trained males (25 \u00b1 5 y) were randomized to supplement 6 g\/day of either betaine anhydrous (BET) or cellulose placebo (PLA) for 14 days. Subsequently, subjects performed four standardized sets of one-leg press and two additional sets to muscular failure on both legs (BFR [LL-BFR; 20% 1RM at 80% arterial occlusion pressure] and high-load [HL; 70% 1RM]). Toe-tip lactate concentrations were sampled before (PRE), as well as immediately (POST0), 30 min (POST30M), and 3 h (POST3H) post-exercise. Serum homocysteine (HCY), growth hormone (GH) and insulin-like growth factor-1 concentrations were additionally assessed at PRE and POST30M. Analysis failed to detect any significant between-supplement differences for total repetitions completed. Baseline lactate changes (\u2206) were significantly elevated from POST0 to POST30 and from POST30 to POST3H (<span class=\"html-italic\">p<\/span>\u00a0&lt; 0.05), whereby HL additionally demonstrated significantly higher \u2206Lactate versus LL-BFR (<span class=\"html-italic\">p<\/span>\u00a0&lt; 0.001) at POST3H. Although serum \u2206GH was not significantly impacted by supplement or condition, serum \u2206IGF-1 was significantly (<span class=\"html-italic\">p<\/span>\u00a0= 0.042) higher in BET versus PLA and serum \u2206HCY was greater in HL relative to LL-BFR (<span class=\"html-italic\">p<\/span>\u00a0= 0.044). Although these data fail to support a BFR-betaine synergy, they otherwise support betaine\u2019s anabolic potential.<\/div>\n<\/section>\n<div id=\"html-keywords\">\n<div class=\"html-gwd-group\">\n<div><\/div>\n<div id=\"html-keywords-title\">Keywords:<\/div>\n<p>arterial occlusion pressure (AOP); blood flow restriction training (BFR); betaine supplementation; resistance training; growth hormone (GH); homocysteine; Hypoxia Inducible Factor-1\u03b1 (HIF-1\u03b1); insulin-like growth factor-1 (IGF-1)<\/p><\/div>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Impacts of Combined Blood Flow Restriction Training and Betaine Supplementation on One-Leg Press Muscular Endurance, Exercise-Associated Lactate Concentrations, Serum Metabolic Biomarkers, and Hypoxia-Inducible Factor-1\u03b1 Gene Expression Steven B. Machek, Dillon R. Harris, Emilia E. Zawieja, Jeffery L. Heileson, Dylan&hellip;&nbsp;<a href=\"http:\/\/www1.up.poznan.pl\/kzcid\/aktualnosci\/nowa-publikacja-20\/\" class=\"more-link\">Czytaj dalej<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[20],"tags":[],"_links":{"self":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1448"}],"collection":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/comments?post=1448"}],"version-history":[{"count":1,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1448\/revisions"}],"predecessor-version":[{"id":1449,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1448\/revisions\/1449"}],"wp:attachment":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/media?parent=1448"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/categories?post=1448"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/tags?post=1448"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}