{"id":1255,"date":"2021-03-16T13:13:34","date_gmt":"2021-03-16T12:13:34","guid":{"rendered":"http:\/\/www1.up.poznan.pl\/kzcid\/?p=1255"},"modified":"2021-03-16T13:13:34","modified_gmt":"2021-03-16T12:13:34","slug":"nowa-publikacja-7","status":"publish","type":"post","link":"http:\/\/www1.up.poznan.pl\/kzcid\/aktualnosci\/nowa-publikacja-7\/","title":{"rendered":"Nowa publikacja"},"content":{"rendered":"<p><strong>Polymorphism of CD36 Determines Fat Discrimination but Not Intake of High-Fat Food in 20- to 40-Year-Old Adults<\/strong><\/p>\n<p>Agata Chmurzynska, Monika A Mlodzik-Czyzewska, Grzegorz Galinski , Anna M Malinowska, Anna Radziejewska, Joanna Miko\u0142ajczyk-Stecyna, Ewa Bulczak, Douglas J Wiebe<\/p>\n<p>&nbsp;<\/p>\n<p>Background: The determinants of the intake of high-fat products are not well understood.<\/p>\n<p>Objective: The aim of this study was to examine the relations between fat perception, intake of high-fat food, and body-weight status, taking into account the polymorphism of the genes that encode the proteins involved in oral fat perception.<\/p>\n<p>Methods: A total of 421 participants aged 20-40 y were enrolled in Pozna\u0144, Poland, from 2016 to 2018. An ascending forced-choice triangle procedure was applied to determine fat discrimination ability. Salad dressings with varying concentrations of canola oil were used as stimuli. Genotyping of rs1761667 (CD36) rs1573611 [free fatty acid receptor 1 (FFAR1)], rs17108973 [free fatty acid receptor 4 (FFAR4)], and rs2274333 (CA6) was performed using TaqMan probes. The frequency of consumption of high-fat foods was measured using an application for mobile devices that uses the ecological momentary assessment approach. The associations were analyzed using linear regression or logistic regression, as appropriate.<\/p>\n<p>Results: Individuals with the GG CD36 genotype were twice as likely to be fat discriminators, compared with the A allele carriers (P &lt; 0.05). The mean total consumption of high-fat food was 45.8 (44.6, 47.0) times\/wk and was not associated with fat discrimination or body-weight status. Obese and overweight subjects ate healthy high-fat food less frequently than did participants with normal body weight, at 4.53 (3.83, 5.23) versus 6.68 (5.82, 7.55) times\/wk, respectively (P &lt; 0.001). Men ate sweet high-fat food and snacks 15% less frequently than did women (P &lt; 0.001 and P &lt; 0.05) but consumed high-fat meat and fast food almost 40% more often than did women (P &lt; 0.001 for both associations).<\/p>\n<p>Conclusions: In individuals aged 20-40 y, fat discrimination ability is associated with polymorphism of CD36 but not with the choice of high-fat food. The frequency of consumption of different types of high-fat foods varies by sex and body-weight status.<\/p>\n<p>Keywords: body weight; fat taste; gene polymorphism; high-fat products.<\/p>\n<p>J Nutr. 2020 Aug 1;150(8):2016-2022. doi: 10.1093\/jn\/nxaa136. PMID: 32455431.<\/p>\n<p>https:\/\/academic.oup.com\/jn\/article-abstract\/150\/8\/2016\/5846209?redirectedFrom=fulltext<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Polymorphism of CD36 Determines Fat Discrimination but Not Intake of High-Fat Food in 20- to 40-Year-Old Adults Agata Chmurzynska, Monika A Mlodzik-Czyzewska, Grzegorz Galinski , Anna M Malinowska, Anna Radziejewska, Joanna Miko\u0142ajczyk-Stecyna, Ewa Bulczak, Douglas J Wiebe &nbsp; Background: The&hellip;&nbsp;<a href=\"http:\/\/www1.up.poznan.pl\/kzcid\/aktualnosci\/nowa-publikacja-7\/\" class=\"more-link\">Czytaj dalej<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[20],"tags":[],"_links":{"self":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1255"}],"collection":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/comments?post=1255"}],"version-history":[{"count":1,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1255\/revisions"}],"predecessor-version":[{"id":1256,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/posts\/1255\/revisions\/1256"}],"wp:attachment":[{"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/media?parent=1255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/categories?post=1255"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www1.up.poznan.pl\/kzcid\/wp-json\/wp\/v2\/tags?post=1255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}